"Project Epoc is a headset that uses a set of sensors to tune into electric signals naturally produced by the brain to detect player thoughts, feelings and expression. It connects wirelessly with all game platforms from consoles to PCs. Project Epoc now makes it possible for games to be controlled and influenced by the player's mind." -- via Kotaku
Speaking of game controllers, here's a force-feedback ForceWear Vest that gives you "physical feedback transmitted from the virtual world". Got shot playing Doom? Get a real-life bruise.