Media Post writes: "Case studies too numerous to count are showing surprising results from the targeted delivery of "out-of-context"online ads - delivering ads to qualified consumers within content areas that are "out-of-context" for the offer."
I'd say it depends on how people get to these content areas in the first place. A good chunk of this blog's traffic comes from Google's search results - these people click mostly on ads related to their search. On the other hand, there are a few fairly constant readers who work in ad agencies (IP domain lookup tells me that). Are they interested in iPods and DVD players? Not if we judge by the click-throughs for the gadget ads. Anyway, here are some thoughts from AdJab that brought the subject up.